Spring 2021

NURS 6302-001 Advanced Pharmacotherapeutics

All students are responsible for checking their UTHSCSA Livemail account regularly (i.e., daily or several times every week) to obtain Official University Communication regarding their courses, program and student status.

Students are expected to follow all policies related to COVID-19 found on the university webpage: https://wp.uthscsa.edu/coronavirus/.

NOTE: Our campus has enabled the CANVAS MOBILE LEARN application. CANVAS tools such as discussions, quizzes or videos May or May NOT function on all mobile devices. This is because mobile devices are available with rapidly changing and different configurations. Hence, students must not depend on only a mobile device to access course materials. Students must have access to a laptop or desktop device to access course materials and complete assignments.

This course is Web Enhanced with WebCT icon
Please be sure to check the Current Computer Requirements

Welcome to Advanced Pharmacotherapeutics! The first day of class will be Friday, January 15 at 1:00 PM. This course will be taught synchronously using a videoconference platform. Make sure you access Canvas and have with you the first week's handout.
See you then,
Dr. Karboski


James A. Karboski, PharmD
Adjunct Professor
Email: karboski@uthscsa.edu
Phone: (512) 232-2628
Office Room: Nursing 2.316
Office Hours: By appointment


This course provides the opportunity to acquire advanced knowledge and skills in the therapeutic use of pharmacologic agents. The pharmacologic treatment of major health problems will be explored. Principles of pharmacokinetics, pharmacodynamics and pharmacogenomics will be examined. The effects of culture, ethnicity, age, pregnancy, gender and funding on pharmacologic therapy will be emphasized. Legal aspects of prescribing will be fully addressed.


Credit Hour Allocation: 3 Semester Credit Hours
Clock Hour Allocation: 3 Clock Hours Class (45 hours class)


NURS 6338 Advanced Pathophysiology


Upon completion of the Master of Science in Nursing Program (MSN) students will:

  1. Integrate scientific findings from nursing and related sciences, including genetics and genomics, into the delivery of advanced nursing care to populations in diverse settings.
  2. Demonstrate organizational and systems leadership to assure ethical and critical decision-making at all systems’ levels for quality and patient safety.
  3. Incorporate performance improvement strategies for quality, safety, and patient-centered care delivery.
  4. Use improvement science to achieve optimal patient care and care environment outcomes.
  5. Integrate meaningful and usable information systems and healthcare technologies to support safe, quality patient care and healthcare systems effectiveness.
  6. Advocate for policy changes that influence healthcare at appropriate levels.
  7. Lead interprofessional teams using collaborative strategies to effect quality patient care and population health outcomes.
  8. Analyze and incorporate broad ecological and social health determinants to design and deliver evidence-based clinical prevention and population healthcare and services to individuals, families, and aggregates/identified populations.
  9. Integrate the advanced competencies expected of a master’s prepared nurse to design, deliver, and evaluate outcomes of systems of care for individuals, families, and diverse populations.


  1. Apply the principles of pharmacology, including pharmacodynamics, pharmacokinetics and pharmacogenomics in the selection and prescription of medication for a variety of patients. (DNP Essentials I, VIII; NONPF Competencies: Scientific Foundation 2, Independent Practice 3)
  2. Design appropriate pharmacologic interventions for treatment of the major health problems. (DNP Essentials I, VIII; NONPF Competency: Independent Practice 3)
  3. Identify potential adverse reactions of pharmacologic agents, including those caused by drug-drug, drug-diet and drug-disease interactions. (DNP Essentials II, III; NONPF Competency: Independent Practice 3, 4)
  4. Select appropriate methods of monitoring effectiveness of pharmacologic therapy. (DNP Essentials I, II, III, IV, VIII; NONPF Competency: Independent Practice 3, 4, 8)
  5. Critically evaluate the appropriateness of pharmacologic therapy in a given client case. (DNP Essentials I, II, III, VIII; NONPF Competency: Independent Practice 3, 4, 8)
  6. Discuss state and federal laws that regulate prescriptive practices. (DNP Essentials II, V; NONPF Competency Independent Practice: 1, 2, 3)
  7. Write appropriate, legally sound medication orders and prescriptions. (DNP Essentials II, III; NONPF Competency: Independent Practice 1, 2, 3)




A = 4 points (90-100)
B = 3 points (80-89)
C = 2 points (75-79)
D = 1 point (66-74)
F = 0 points (65 or below)


Your individual score will be based upon the following items:

Weekly Quizzes: 80%
Final Examination (must take if quiz average <80%): 20%

Your individual grade will be based on the following scale:

A 90 -100%
B 80 -89%
C 70 -79%
D 60 -69%
F Below 60%



Attendance in class is an expectation of each student.


  1. If written assignments are made in a course they are required.
  2. Students are expected to submit written work on the scheduled date and time.
  3. The student must notify the course coordinator prior to the scheduled due date and time if they are unable to submit the written work as scheduled. Failure to make this notification in advance will result in a "zero" for that written work.
  4. If the excuse is accepted as reasonable and necessary, arrangements will be made for an alternative due date and time.
  5. Each student is responsible for making sure that he or she has completed the written work prior to submission.
  6. Late work will be accepted with consequences as outlined per course syllabi.


The APA Publication Manual 7th edition is required for use in all nursing school programs. 


Students are expected to be above reproach in all scholastic activities. Students who engage in scholastic dishonesty are subject to disciplinary penalties, including the possibility of failure in the course and dismissal from the university. "Scholastic dishonesty includes but is not limited to cheating, plagiarism, collusion, and submission for credit of any work or materials that are attributable in whole or in part to another person, taking an examination for another person, any act designed to give unfair advantage to a student or the attempt to commit such acts." Regents Rules and Regulations, Part One, Chapter VI, Section 3, Subsection 3.2, Subdivision 3.22.


Students who are nurses or are preparing to enter the profession of nursing are expected to treat others with respect and compassion. “The principle of respect for persons extends to all individuals with whom the nurse interacts. The nurse maintains compassionate and caring relationships with colleagues and others with a commitment to the fair treatment of individuals, to integrity-preserving compromise and to resolving conflict. This standard of conduct precludes any and all prejudicial actions, any form of harassment or threatening behavior, or disregard for the effects of one’s actions on others” (American Nurses Association Code for Nurses, Interpretive Statement 1.5).

The students, faculty, Department Chairs, Associate Deans, and the Dean of the School of Nursing of the University Texas Health Science Center San Antonio subscribe to the highest standards of conduct. Our aim is professional behavior beyond reproach. Failure to abide by the signed code of professional conduct may lead to suspension and/or permanent dismissal from the UTHSCSA SON. In particular, we subscribe to the provisions of the Code of Ethics for Nurses (http://bit.ly/1mtD5p2) and the following points of conduct.


School of Nursing Netiquette Guidelines for Online Interaction

Netiquette guidelines provide information for behaving properly online, when using email, tweets or texts so that you may successfully communicate your thoughts in a manner that is respectful and avoids misunderstandings with others.


Any student seeking reasonable accommodations through the Americans with Disabilities Act (ADA) should contact either the Associate Dean for Admissions and Student Services within the first week of the semester or schedule a meeting with the UTHSCSA ADA Compliance Office so that appropriate accommodations may be arranged. A request for accommodations (Form ADA-100: http://uthscsa.edu/eeo/form100-Faculty-student-resident.pdf) must be completed and submitted to the Executive Director of the ADA Compliance Office before accommodations can be provided. Additional information can be provided in the Student Success Center, Room 1.118 or through the ADA Compliance Office website: http://uthscsa.edu/eeo/request.asp.


None.  See list of Recommended References.


Information Sources (Not Required)

1."Pharmacotherapy: A Pathophysiologic Approach" 11th edition, by Dipiro, Talbert, Yee, Matzke, Wells and Posey. ISBN: 978-1259587481

2."Pharmacotherapy: Principles & Practice” by Chisholm-Burns, Wells, Schwinghammer and others. ISBN: 978-1260019445


January 15Fundamentals & Pharmacology
January 22Pharmacokinetics & Drug Interactions
January 29Heart Failure
February 5Hypertension/Lipids
February 12Contraception
February 19Respiratory Disorders
February 26Gastrointestinal Disorders
March 5Psychiatric Disorders
March 19Diabetes
March 26Antibiotic Classification
April 2Infectious Diseases
April 9Analgesics
April 16Antithrombotic Therapy
April 30TBA

CALENDAR - 1st Day Only

Please check the schedule for recent updates on Class Dates & Room.

Welcome to Advanced Pharmacotherapeutics! The first day of class will be Friday, January 15 at 1:00 PM. This course will be taught synchronously using a videoconference platform. Make sure you access Canvas and have with you the first week's handout.
See you then,
Dr. Karboski

© School of Nursing | The University of Texas Health Science Center at San Antonio external link
Links provided from Health Science Center School of Nursing pages to other websites do not constitute or imply an endorsement of those sites, their content, or products and services associated with those sites.

School of Nursing - UT Health Science Center San Antonio